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For laboratory research use only
Mitochondrial Activator
MOTS-c
10mg · Lyophilised Powder
$109.00
MOTS-c is a mitochondria-encoded peptide that acts as a metabolic regulator — improving insulin sensitivity, activating AMPK pathways, and supporting the energy metabolism women lose as oestrogen declines and mitochondrial efficiency deteriorates.
Key Highlights
10mg MOTS-c per vial — lyophilised for stability
≥99% purity, HPLC-verified
Mitochondria-encoded peptide — unique in peptide science
Activates AMPK metabolic pathway
Studied for insulin sensitivity improvement
Sterile glass vial, GMP-certified manufacture
Why This Compound Matters for Women
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a small peptide encoded within the mitochondrial genome — making it one of the only known peptides of mitochondrial origin. This distinction is significant: it means MOTS-c can act as a direct messenger between mitochondria and the rest of the cell, regulating metabolic responses to nutritional and physiological stress. Research has focused primarily on its ability to improve insulin sensitivity, activate AMPK (AMP-activated protein kinase), and regulate glucose and fatty acid metabolism. For women, MOTS-c is particularly compelling because perimenopause is characterised by a progressive decline in mitochondrial efficiency, increasing insulin resistance, and a shift in fat distribution toward visceral accumulation. MOTS-c has also been studied in the context of exercise performance and muscle preservation — two areas where women face specific challenges as they age. It is one of the most exciting emerging compounds in women's longevity research.
Research Areas
For research context only. All applications are laboratory use.
Insulin Sensitivity & Glucose Metabolism
MOTS-c is studied for its significant effects on insulin sensitivity and glucose utilisation — directly addressing the metabolic resistance that becomes more prevalent in women post-perimenopause.
AMPK Pathway Activation
AMPK is often called the 'metabolic master switch'. MOTS-c's activation of this pathway is studied for its downstream effects on energy balance, fat oxidation, and cellular longevity.
Mitochondrial Communication
As a mitochondria-derived peptide, MOTS-c is uniquely positioned to signal directly from the cell's energy centres — research explores how this communication pathway supports systemic metabolic health.
Muscle Preservation & Exercise Performance
Studies investigate MOTS-c in the context of muscle fibre maintenance and exercise metabolism — relevant for women managing sarcopenia (age-related muscle loss) during hormonal transition.
Specifications
Research Use Only. Not intended for human or veterinary use. Handle with sterile technique. Store refrigerated between 2–8°C.